User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
User error: "attributes" is an invalid render array key in Drupal\Core\Render\Element::children() (line 97 of core/lib/Drupal/Core/Render/Element.php).
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UMGANG MIT COVID-19 – Wir setzen uns dafür ein, unsere wissenschaftliche Gemeinschaft während dieser Pandemie zu unterstützen. Mehr erfahren

High-Content-Screening mit der AgileOptix™ Technologie

Leistungsstarke Solid-State-Laser, Wasserimmersionsobjektive, Scientific-CMOS-Sensor und Dual-Spinning-Disk mit fünf verschiedenen Disk-Geometrien

Hochdurchsatz-,High-Content-Screeninglösung für die komplexe 3D-Biologie

Die ImageXpress® Confocal Systeme bieten die revolutionäre AgileOptix™ Spinning-Disk-Technologie für das High-Content-Screening (HCS). Diese ermöglicht nutzerdefinierte Konfigurationen, um sowohl für das konfokale als auch das Weitwinkel-Imaging die maximale Assay-Leistung sicherzustellen. Es stehen mehrere konfokale Geometrien zur Verfügung, darunter konfokales Imaging mit Lochblende und Spaltblende – das einzige kommerziell erhältliche High-Content-Imaging-System mit diesen Optionen.

Die HCS-Technologie des AgileOptix™ ermöglicht es dem System, die Empfindlichkeit und den Durchsatz bereitzustellen, die für anspruchsvolle Anwendungen erforderlich sind, indem es eine fortschrittliche Solid-State-Lichtmaschine, eine firmeneigene Spinning-Disk-Technologie, hochmoderne Optik und einen Scientific-CMOS-Sensor kombiniert. Das System erfasst einen dynamischen Bereich von > 3 log und nimmt Bilder in Publikationsqualität auf, während sein großes optisches Sichtfeld die Erfassung statistisch relevanter Daten maximiert.

Erhöhen Sie die Imaging-Effizienz, indem Sie die intelligente „QuickID gezielte Bildaufnahme“-Funktion nutzen, die von unserer MetaXpress® Software ausgeführt wird. Für die Analyse komplexer 3D-Biologie mithilfe künstlicher Intelligenz (KI) bietet die IN Carta Bildanalyse-Software einen optimierten Arbeitsablauf mit leistungsstarker, auf Deep-Learning basierender Segmentierung, mit auf maschinellem Lernen basierender Klassifizierung und mit volumetrischer 3D-Analyse.

Molecular Devices kann das ImageXpress Confocal System erfolgreich maßschneidern, um die hier beschriebenen Funktionen in benutzerspezifische Software und Hardware mit zu integrieren, ebenso wie andere Laborkomponenten, z. B. Inkubatoren, Pipettierroboter und Roboter für voll automatisierte Arbeitszellen. Entdecken Sie unser neues Organoid Innovation Center, in dem wir diese hochmodernen Technologien mit ihren neuartigen Methoden für die 3D-Biologie vorstellen, um die wichtigsten Herausforderungen bei der Skalierung komplexer 3D-Biologie zu meistern.

Der Vertrieb unterliegt unseren Kaufbedingungen für benutzerdefinierte Produkte, einzusehen unter www.moleculardevices.com/custom-products-purchase-terms

Erfahren Sie, wie Sie die Herausforderungen des Hochdurchsatz-3D-Imagings und der -analyse meistern können

Unser High-Content-Screening-System mit AgileOptix™ Technologie stellt eine vollständig integrierte Lösung dar, die die vielen Herausforderungen überwindet, die mit dem Hochdurchsatz-3D-Imaging verbunden sind. Angefangen mit Trübungen durch Licht außerhalb des Fokus oder Schwierigkeiten bei der Lichtdurchdringung bis hin zu Analyse-Engpässen und Schwierigkeiten bei der High-Content-Datenauswertung haben wir haben die Lösung für Sie. Aufgrund unserer über 35 Jahre langen Erfahrung in der Life-Science-Branche können Sie sich darauf verlassen, dass wir Qualitätsprodukte liefern und weltweite Unterstützung bieten.

3D-Zellmodelle

3D-Zellkulturen bieten den Vorteil, dass sie die Aspekte menschlicher Gewebe, einschließlich der Architektur, Zellorganisation, der Zell-Zell- und Zell-Matrix-Interaktionen und physiologisch relevantere Diffusionsmerkmale besser nachstellen. Die Anwendung von zellulären 3D-Assays ermöglicht eine zusätzliche Wertschöpfung aus Forschungs- und Screeningprojekten und überbrückt so die translationale Lücke zwischen 2D-Zellkulturen und Tiermodellen. Indem sie wichtige Parameter der in vivo-Umgebung reproduzieren, können 3D-Modelle einzigartige Einblicke in das Verhalten von Stammzellen und sich entwickelnden Geweben in vitro liefern.

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Zelluläres Imaging und Analyse

Forschern stehen dabei mehrere Optionen für Zell-Imaging-Methoden zur Verfügung, angefangen bei der Phasenkontrast-Mikroskopie, die intakte Zellen abbildet, bis hin zum Fluoreszenz-Imaging, das einzelne Moleküle und Organellen darstellt. Eine zelluläre Analyse wird durchgeführt, um den aktuellen Zustand der Zellen zu messen und zu beurteilen, wie z. B. die Zellintegrität, Toxizität und Überlebensfähigkeit und verschiedene andere Forschungsanwendungen. Ein wesentlicher Teil der zellulären Analyse ist die Erfassung, Analyse und der Export von Daten in einem aussagekräftigen und nutzenbringenden Format.

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Zelluläre Imaging-Systeme

Unsere Systeme für das High-Content-Imaging (HCI) und die High-Content-Analyse (HCA) bieten eine flexible Skalierbarkeit, die es einfach macht, Ihr System im Gleichschritt mit Ihrer Forschung weiter auszubauen. Sie verfügen über Optionen und Module, mit denen Ihre spezielle Forschung adressiert werden kann, darunter Objektive, Filter, Imaging-Modi und Umgebungsbedingungen. Alle unsere Systeme unterstützen eine große Bandbreite an Anwendungen, erhöhten Durchsatz und optimierte Arbeitsabläufe.

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Organoid Innovation Center

Das neue Organoid Innovation Center von Molecular Devices kombiniert modernste Technologien mit neuartigen Methoden der 3D-Biologie, um die wichtigsten Herausforderungen der Skalierung der komplexen 3D-Biologie zu lösen.

Der Teamarbeitsbereich bringt Kunden und Forscher gemeinsam ins Labor, um automatisierte Arbeitsabläufe für die Kultivierung und das Screening von Organoid-Kulturen zu testen – unter Anleitung unserer betriebsinternen Wissenschaftler.

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Ressourcen für das High-Content-Screening mit der AgileOptix™ Technologie

Broschüre

ImageXpress Confocal HT.ai

ImageXpress Confocal HT.ai

Das ImageXpress® Confocal HT.ai High-Content Imaging System nutzt eine Laser-Lichtquelle mit sieben Kanälen und acht Imaging-Kanäle, um hochgradig multiplexe Assays zu ermöglichen – bei gleichzeitiger Aufrechterhaltung …

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Hochleistungs-Anpassung

High-performance Customizations

Erfassen Sie mehr Daten bei größeren Tiefen in 3D-Geweben und dicken Gewebeproben: Skalierbare, Hochleistungs-, High-Content-Screeninglösungen mit dem ImageXpress® Micro Confocal System

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Wissenschaftliche Poster

Einsatz einer Laser-Lichtquelle für das automatisierte High-Content-Imaging

Using a laser light source for high-content automated imaging

In dieser Studie demonstrieren wir Verbesserungen in der Assay-Empfindlichkeit, der Aufnahme-Präzision und -Geschwindigkeit mithilfe einer neuen Konfiguration des ImageXpress® Confocal HT.ai High-Content Imaging …

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Application Note

Verbessern Sie die Empfindlichkeit, Geschwindigkeit und Qualität für komplexe biologische Assays

Improve sensitivity, speed, and assay quality for complex biological assays

Hier demonstrieren wir Verbesserungen in der Assay-Empfindlichkeit, der Assay-Qualität und der Assay-Geschwindigkeit mithilfe des laserbasierten ImageXpress® Confocal HT.ai High-Content Imaging Systems.

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Application Note

3D-Bildanalyse und Charakterisierung der Angiogenese in einem Organ-on-a-Chip-Modell

3D image analysis and characterization of angiogenesis in organ-on-a-chip model

Angiogenese ist der physiologische Prozess der Bildung und Umgestaltung neuer Blutgefäße und Kapillaren aus bereits existierenden Blutgefäßen. Dies kann durch endotheliale …

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Application Note

Überwachen Sie die die Dynamik und den Phänotyp von Mitochondrien mittels High-Content-Imaging

Monitor mitochondria dynamics and phenotype with high-content imaging

Mitochondrien stellen für Zellen die Haupt-Energielieferanten dar und spielen eine wichtige Rolle bei der Regulation des Stoffwechsels. Mitochondrien können ihre Struktur in Anhängigkeit von den Umgebungsbedingungen …

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Wissenschaftliche Poster

Wasserimmersionsobjektive für das automatisierte High-Content-Imaging, zur Verbesserung der Präzision und Qualität komplexer biologischer Assays

Water immersion objectives for automated high-content imaging to improve precision and quality of complex biological assays

Der Zweck dieser Studien war zu bestimmen, ob Wasserimmersionsobjektive, die zur Verbesserung der Bildqualität in komplexen biologischen Assays genutzt wurden, in einer High-Throughput-Umgebung eingesetzt werden können.

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Flyer

Wasserimmersionsobjektive für das ImageXpress Micro Confocal System

Water Immersion Objectives for the ImageXpress Micro Confocal system

Steigern Sie die Empfindlichkeit, um mehr phänotypische Daten bei größeren Tiefen aufzunehmen. Unsere High-Content-Imager und unser Expertenteam stehen bereit, um Ihrem Labor bei der Vereinfachung der Aufnahme und Analyse komplexer, 3D- …

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Application Note

Nehmen Sie die Daten von 3D-Sphäroiden, die in Symphoid® und VersaGel® kultiviert wurden, 10x schneller auf

Acquire data 10X faster from 3D spheroids cultured using Symphony® and VersaGel®

Die meisten in vitro Zellkulturarbeiten werden zweidimensional (2D) durchgeführt, wobei Zellen flach auf einer Oberfläche wachsen. Zellen mit dem Ziel des Wirkstoffscreenings in 2D zu kultivieren, liefert ein eingeschränktes Bild …

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Broschüre

Imaging-Lösungen, um Ihre biologischen Fragestellungen zu beantworten

Imaging Solutions to Answer Your Biological Questions

Erfahren Sie mehr über unsere Imaging-Familie und darüber, welche Lösung zur Beantwortung Ihrer biologischen Fragestellungen am besten geeignet ist.

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Videos und Webinare

Wasserimmersionsobjektive & High-Content-Imaging

Gewinnen Sie mit Wasserimmersionsobjektiven tiefere Einblicke in 3D-Zellstrukturen

Zugehörige Produkte und Service für das High-Content-Screening mit der AgileOptix™ Technologie

Wie können wir Sie dabei unterstützen, Ihre nächste große Entdeckung voranzubringen?

Unsere hochqualifizierten Teams unterstützen unsere Kunden an der Front, führen Produktdemonstrationen vor Ort oder per Fernzugriff durch und bieten Webinare und mehr, um Ihnen bei der Lösung ihrer besonderen Forschungsherausforderungen zu helfen. Wie können wir Sie heute unterstützen?

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High-Content-Screening mit der AgileOptix™ Technologie

Hochdurchsatz-,High-Content-Screeninglösung für die komplexe 3D-Biologie

Erfahren Sie, wie Sie die Herausforderungen des Hochdurchsatz-3D-Imagings und der -analyse meistern können

Mehr großartige Ressourcen

3D-Zellmodelle

Zelluläres Imaging und Analyse

Zelluläre Imaging-Systeme

Organoid Innovation Center

Ressourcen für das High-Content-Screening mit der AgileOptix™ Technologie

Videos und Webinare

Zugehörige Produkte und Service für das High-Content-Screening mit der AgileOptix™ Technologie

Wie können wir Sie dabei unterstützen, Ihre nächste große Entdeckung voranzubringen?