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On-demand Webinar |
Implementing 3D neural spheroids in drug discovery
We detail how the FLIPR® Penta system and the ImageXpress® Micro Confocal system have been used to functionally and structurally characterize StemoniX® microBrain® 3D spheroids from both healthy and disease sources.
- Use of microBrain neuronal microspheroids
- Calcium oscillations in neural spheroids
- 3D image analysis of compound treated neural spheroids
- Multi-parametric evaluation of neurotoxicity effects
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Application Spotlight |
Monitor mitochondria dynamics and phenotype with high-content imaging
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Mitochondria are the main energy source for cells and play a key role in regulating cellular metabolism. Mitochondria can change their structures depending on environmental conditions and cellular requirements. There has been growing interest in using high-content imaging methods for studying the mitochondrial structure remodeling.
Learn how to achieve enhanced image quality and better visualization of mitochondria dynamics using the ImageXpress Micro Confocal system. |
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Customer Spotlight |
University of Leeds |
For the Tomlinson lab at the University of Leeds, UK, the ImageXpress Pico® Automated Cell Imaging System was the perfect choice for small-scale screening. They use a novel protein recognition tool, called an ‘affimer’, to study and understand protein function at the molecular level. |
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Virtual Tour |
ImageXpress Nano Automated Imaging System |
Join our Bioimaging Field Applications Scientist, Kayla Hill, PhD, for a virtual tour of the ImageXpress® Nano system—a widefield fluorescence imaging platform designed for powerful image acquisition, review, and analysis. |
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On-demand Webinar |
Accelerating study of viral infection and therapeutics |
View this webinar and learn how to:
- Integrate microplate reader detection and high-content screening workflows for detection of viral infectivity, investigation of viral mechanism of action, and screening of therapies
- Use high-throughput screening to analyze multiple parameters across RNAi, therapeutic vaccine, and antibody screens
- Determine viral infectivity TCID50 through fluorescence, luminescence, or absorbance-based microplate detection platforms
- Establish robust assays across multiple platforms for high-throughput detection of viral infectivity with microplate detection and high-content imaging applications
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Application Spotlight |
Luminescence |
Cancer studies often utilize luminescence-based methods for measuring parameters such as cell viability in response to drug treatment, and biomolecular interactions occurring in response to stimulation of cell signaling pathways.
Learn how the SpectraMax® iD5 Multi-Mode Microplate Reader yields optimal results for luminescence assays.
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Application Spotlight |
Angiogenesis |
Angiogenesis, an important factor in cancer progression, is often investigated in vitro with tube formation assays, and in vivo using zebrafish as a model system. However, scaling up these assays for screening poses significant challenges for image acquisition and analysis.
Learn how the ImageXpress® high-content imaging system can help you with your angiogenesis research. |
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EVENTS |
PEGS
August 31-September 4, 2020 l Boston, MA USA
LabDays Copenhagen
September 2-3, 2020 l Copenhagen, Denmark
Organ-on-a-Chip, Tissue on a Chip & Organoids
September 9-10, 2020 l Rotterdam, The Netherlands
SBI2 - Virtual
September 16-17, 2020 l North America
Discovery on Target - Virtual
September 16-18, 2020 l Boston, MA USA
Analytica
October 19-22, 2020 l Munich, Germany
Neuroscience
October 24-28, 2020 l Washington, D.C., USA
Cell Bio
December 5-9, 2020 l Philadelphia, PA USA |
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