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Automated 3D cell-based assays using a novel flowchip system and high-content imaging

This poster outlines:

  • Capabilities of a novel automated 3D cell-based assay system that performs complex protocols with 3D cell models in an incubator environment.
  • Cancer spheroid treatments were assayed using high resolution confocal imaging of spheroids incubated with various compounds and live/dead staining and analysis.
  • Automated neurospheroid treatments were performed with the Pu•MA System. Compatibility with the FLIPR Penta system allows multiple measurements of individual spheres with minimal time outside an incubator environment.
  • Ability to analyze spheroids and organoids in situ in order to capture toxicity information and perform functional assays shows great promise for drug discovery.

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